5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid CAS 1040006-05-0
| CAS No. | 1040006-05-0 |
| Molecular Formula | C13H10ClFN2O2 |
| Molecular Weight | 280.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 280.68 g/mol gives 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid (CAS 1040006-05-0), molecular formula C13H10ClFN2O2 and molecular weight 280.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid (C13H10ClFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 280.68 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClFN2O2 |
| Molecular Weight | 280.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 5-Chloro-2-((3-fluorobenzyl)oxy)benzoic acid (CAS 1002312-89-1)
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- 1-(3-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1038738-53-2)
- 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041536-98-4)
- 3-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041558-34-2)
- 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1082401-01-1)
- 3-Chloro-5'-fluoro-2'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1097085-11-4)
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Recommended Standards
- N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 430454-70-9)
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- 5-Chloro-1-(3-(trifluoromethoxy)phenyl)pentan-1-one (CAS 898786-25-9)
- 1-(4-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1152536-23-6)
- 1-ethyl-3-methyl-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 31217-72-8)
- 3-(trimethoxymethyl)isoquinolin-1(2H)-one (CAS 847783-41-9)
- 2,4-Difluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1451391-16-4)
- N,3,3-trimethyl-2-(3-(p-tolyl)ureido)butanamide (CAS 477768-35-7)
- (4-(Butylcarbamoyl)phenyl)boronic acid (CAS 252663-48-2)
- (3AR,4R,6aR)-4-decyl-3-methylenedihydrofuro[3,4-b]furan-2,6(3H,6aH)-dione (CAS 154674-22-3)
- (5-Bromo-1-methyl-1H-pyrazol-3-yl)methanol (CAS 1782396-26-2)
- n-Octylzinc bromide 0.5 M in Tetrahydrofuran (CAS 131379-13-0)
- 4-[4-(Aminomethyl)pyridin-2-yl]-1lambda(6),4-thiomorpholine-1,1-dione (CAS 1153843-40-3)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
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