4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid CAS 1041536-98-4
| CAS No. | 1041536-98-4 |
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041536-98-4), a certified reference material (molecular formula C14H10ClFO3, MW 280.68 g/mol) for analytical method development and quality control.
The molecular framework of 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (C14H10ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-((3-fluorobenzyl)oxy)benzoic acid (CAS 1002312-89-1)
- 2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1019348-55-0)
- 1-(3-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1038738-53-2)
- 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid (CAS 1040006-05-0)
- 3-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041558-34-2)
- 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1082401-01-1)
- 3-Chloro-5'-fluoro-2'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1097085-11-4)
- 2-(3-chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1097168-10-9)
Recommended Standards
- N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 430454-70-9)
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- 5-Chloro-1-(4-(trifluoromethoxy)phenyl)pentan-1-one (CAS 898761-63-2)
- 1-(5-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1156854-36-2)
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