(3-Chloro-2,6-difluorophenyl)boronic acid CAS 1031226-45-5
| CAS No. | 1031226-45-5 |
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (3-Chloro-2,6-difluorophenyl)boronic acid (CAS 1031226-45-5), a certified reference material (molecular formula C6H4BClF2O2, MW 192.36 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (3-Chloro-2,6-difluorophenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (4-Chloro-2,3-difluorophenyl)boronic acid (CAS 1160561-28-3)
- (3-Chloro-2,4-difluorophenyl)boronic acid (CAS 1310384-18-9)
- 2-Chloro-4,6-difluorophenylboronic Acid (CAS 1373393-48-6)
- (2-Chloro-3,5-difluorophenyl)boronic acid (CAS 1451393-37-5)
- (3-Chloro-4,5-difluorophenyl)boronic acid (CAS 1643467-84-8)
- 2-Chloro-4,5-difluorophenylboronic acid (CAS 1801916-39-1)
- (4-Chloro-2,6-difluorophenyl)boronic acid (CAS 925911-61-1)
- 2-Chloro-3,4-difluorophenylboronic acid (CAS 2121511-30-4)
Recommended Standards
- 2-(Caboxymethylthio)ethyltrimethylsilane (CAS 18269-42-6)
- CAS 25232-08-0 (CAS 25232-08-0)
- tetradecahydroanthracene (CAS 6596-35-6)
- 2,3-Difluoro-6-chlorophenylboronic acid (CAS 1310404-70-6)
- 6-(tert-Butyl)chroman-4-one (CAS 23067-77-8)
- 5,7-Dichloro-1H-indazole (CAS 50477-27-5)
- 1-(3-Chlorophenyl)-2-fluoroethan-1-ol (CAS 40733-92-4)
- 2-Amino-N-[2-(dimethylamino)ethyl]-2-methylpropanamide Dihydrochloride (CAS 1219957-57-9)
- 4-Chloro-N-(4-chloropyrimidin-5-yl)-3-cyanobenzamide (CAS 918880-63-4)
- Pyrrolo[1,2-a]pyrimidin-3-ylamine dihydrochloride (CAS 2379651-47-3)
- 2,2'-Diethynyl-1,1'-biphenyl (CAS 18442-29-0)
- (3,5-Dimethylisoxazol-4-yl)methanamine hydrochloride (CAS 503469-65-6)
- 4-Methyl-5-(4-piperidinyl)-2-pyridinamine (CAS 1260857-55-3)
- Palmitoyl Tripeptide-1 TFA salt (CAS 2803375-47-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com