(3-Chloro-4,5-difluorophenyl)boronic acid CAS 1643467-84-8
| CAS No. | 1643467-84-8 |
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (3-Chloro-4,5-difluorophenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(3-Chloro-4,5-difluorophenyl)boronic acid (CAS 1643467-84-8) is a high-purity analytical reference standard with the molecular formula C6H4BClF2O2 and a molecular weight of 192.36 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluorophenyl)boronic acid (CAS 1031226-45-5)
- (4-Chloro-2,3-difluorophenyl)boronic acid (CAS 1160561-28-3)
- (3-Chloro-2,4-difluorophenyl)boronic acid (CAS 1310384-18-9)
- 2-Chloro-4,6-difluorophenylboronic Acid (CAS 1373393-48-6)
- (2-Chloro-3,5-difluorophenyl)boronic acid (CAS 1451393-37-5)
- 2-Chloro-4,5-difluorophenylboronic acid (CAS 1801916-39-1)
- (4-Chloro-2,6-difluorophenyl)boronic acid (CAS 925911-61-1)
- 2-Chloro-3,4-difluorophenylboronic acid (CAS 2121511-30-4)
Recommended Standards
- 2,3-Difluoro-6-chlorophenylboronic acid (CAS 1310404-70-6)
- 2-Chloro-3,6-difluorophenylboronic acid (CAS 2377608-42-7)
- 3-Chloro-2,5-difluorophenylboronic acid (CAS 2377610-17-6)
- 4-Chloro-2,5-difluorophenylboronic acid (CAS 2055778-26-0)
- 3-Pyridinecarboxaldehyde-d (CAS 258854-80-7)
- tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate (CAS 1557780-95-6)
- 3-(2,5-Difluorobenzyl)piperidin-3-ol (CAS 1341505-30-3)
- 2-((3-Bromo-[1,1'-biphenyl]-4-yl)oxy)acetic acid (CAS 625820-74-8)
- 3-Isobutyrylbenzaldehyde (CAS 1267425-02-4)
- 2-Amino-2-methylcyclohexane-1-carboxylic acid hydrochloride (CAS 1423025-63-1)
- (E)-2-styrylbenzo[d]oxazole (CAS 78685-70-8)
- 7-Bromo-n-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-5-ethyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carboximidamide (CAS 1714146-64-1)
- 4-Trifluoromethanesulfonylbenzene-1-sulfonyl chloride (CAS 63647-64-3)
- Semaglutide Impurity 5 (CAS 23406-82-8)
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