2-Chloro-3,4-difluorophenylboronic acid CAS 2121511-30-4
| CAS No. | 2121511-30-4 |
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Chloro-3,4-difluorophenylboronic acid (C6H4BClF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 192.36 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Chloro-3,4-difluorophenylboronic acid (CAS 2121511-30-4), molecular formula C6H4BClF2O2 and molecular weight 192.36 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-3,4-difluorophenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluorophenyl)boronic acid (CAS 1031226-45-5)
- (4-Chloro-2,3-difluorophenyl)boronic acid (CAS 1160561-28-3)
- (3-Chloro-2,4-difluorophenyl)boronic acid (CAS 1310384-18-9)
- 2-Chloro-4,6-difluorophenylboronic Acid (CAS 1373393-48-6)
- (2-Chloro-3,5-difluorophenyl)boronic acid (CAS 1451393-37-5)
- (3-Chloro-4,5-difluorophenyl)boronic acid (CAS 1643467-84-8)
- 2-Chloro-4,5-difluorophenylboronic acid (CAS 1801916-39-1)
- (4-Chloro-2,6-difluorophenyl)boronic acid (CAS 925911-61-1)
Recommended Standards
- 2-Chloro-3,6-difluorophenylboronic acid (CAS 2377608-42-7)
- 3-Chloro-2,5-difluorophenylboronic acid (CAS 2377610-17-6)
- 4-Chloro-2,5-difluorophenylboronic acid (CAS 2055778-26-0)
- 4-Chloro-3,5-difluorophenylboronic Acid (CAS 864759-63-7)
- 3-Azetidinyl 2-methoxy-4-propylphenyl ether (CAS 1219982-47-4)
- (1R,2S)-2-(2-(2-nitrophenyl)-2-oxoethyl)cyclohexane-1-carboxylic acid (CAS 735275-01-1)
- Methyl (tert-butoxycarbonyl)-D-phenylalanyl-L-leucinate (CAS 129279-71-6)
- 4-(2,3-Dichlorophenyl)thiazol-2-amine (CAS 886494-98-0)
- 2-(Aminomethyl)-[1,2,4]triazolo[1,5-a]pyrimidine Hydrochloride (CAS 1896825-95-8)
- Gold, (pentachlorophenolato)(triphenylphosphine)- (CAS 118153-91-6)
- 1-(2,2-Difluoroethyl)-4-iodo-5-methyl-1H-pyrazol-3-amine (CAS 1354706-79-8)
- (3S,4S)-4-isobutylpyrrolidine-3-carboxylic acid hydrochloride (CAS 641634-62-0)
- Ethyl 2-Oxazolecarboxylate (CAS 33036-67-8)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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