Levofloxacin Impurity N27 CAS 1036016-10-0
| CAS No. | 1036016-10-0 |
| Molecular Formula | C18H21F2N3O4 |
| Molecular Weight | 381.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Levofloxacin Impurity N27 (C18H21F2N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Levofloxacin Impurity N27 (CAS 1036016-10-0), a pharmacopoeial impurity reference standard (molecular formula C18H21F2N3O4, MW 381.37 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Levofloxacin Impurity N27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21F2N3O4 |
| Molecular Weight | 381.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Levofloxacin Standards
- Levofloxacin Impurity 92 (CAS CATO-C4X-137192)
- Levofloxacin EP Impurity C(Levofloxacin N-Oxide) (CAS 117678-38-3)
- (R)-Levofloxacin N-Oxide (CAS 117678-37-2)
- Levofloxacin Impurity 52 (CAS 1152314-62-9)
- Levofloxacin Impurity 88 (CAS CATO-C4X-137188)
- Levofloxacin Impurity 34 (CAS 108224-82-4)
- Levofloxacin Impurity 40 (CAS 106939-30-4)
- Levofloxacin Methyl Ester (CAS 862690-19-5)
Recommended Standards
- 6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidyl]nicotinamide (CAS 1033836-12-2)
- tert-Butyl 6-(trifluoromethylsulfonyloxy)-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 158984-84-0)
- Metsulfuron-Methyl (CAS 74223-64-6)
- Ethyl 1-(4-(p-tolyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 159885-65-1)
- Caspofungin EP Impurity A (CAS 1202167-57-4)
- Ponatinib Impurity 36 (CAS CATO-C4X-226936)
- Lercanidipine Impurity 72 (CAS 320750-11-6)
- N-(heptan-4-yl)-1-methylpiperidin-4-amine (CAS 1096338-21-4)
- (2Z)-2-Phenyl-3-{6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}prop-2-enenitrile (CAS 338404-76-5)
- 5,8-Dichloro-4-hydrazinylquinoline hydrochloride (CAS 1170215-21-0)
- 2-(3-(4-Chlorophenyl)ureido)thiazole-4-carboxylic acid (CAS 941869-64-3)
- N-(4-(1-Acetyl-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide (CAS 852141-13-0)
- (2-(Azetidin-1-ylmethyl)phenyl)(4-bromophenyl)methanone (CAS 898754-71-7)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com