Levofloxacin Impurity 52 CAS 1152314-62-9
| CAS No. | 1152314-62-9 |
| Molecular Formula | C17H17FN4O5 |
| Molecular Weight | 376.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Levofloxacin Impurity 52 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Levofloxacin Impurity 52 (CAS 1152314-62-9) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17FN4O5 and a molecular weight of 376.34 g/mol.
Structurally, Levofloxacin Impurity 52 (C17H17FN4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 376.34 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Levofloxacin Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17FN4O5 |
| Molecular Weight | 376.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Levofloxacin Standards
- Levofloxacin Impurity 88 (CAS CATO-C4X-137188)
- Levofloxacin Impurity 34 (CAS 108224-82-4)
- Levofloxacin Impurity 40 (CAS 106939-30-4)
- Levofloxacin Methyl Ester (CAS 862690-19-5)
- Levofloxacin impurity 78 (CAS 107359-24-0)
- Levofloxacin Impurity 83 (CAS 1268719-66-9)
- Levofloxacin EP Impurity C(Levofloxacin N-Oxide) (CAS 117678-38-3)
- (R)-Levofloxacin N-Oxide (CAS 117678-37-2)
Recommended Standards
- Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin, 4-hydroxy-2,6-dimethyl-, 4-oxide (CAS 65355-16-0)
- (1S,2S)-N1,N2-Dimethyl-1,2-bis(4-(trifluoromethyl)phenyl)ethane-1,2-diamine (CAS 2640520-10-9)
- N-Nitroso N-Desmethyl Ofloxacin (CAS CATO-C4X-171712)
- (1R,2R)-N1,N2-Dimethyl-1,2-bis(4-(trifluoromethyl)phenyl)ethane-1,2-diamine (CAS 220665-47-4)
- Ipratropium Bromide EP Impurity D (CAS 492-38-6)
- Roflumilast Impurity 10 (CAS 127842-54-0)
- Posaconazole Impurity 278 (CAS CATO-C4X-1208278)
- 2-(Piperidin-1-ylmethyl)quinazolin-4(3H)-oneHydrochloride (CAS 3552-63-4)
- Methyl 2-(1-((tert-butoxycarbonyl)amino)cyclohexyl)propanoate (CAS 2745062-28-4)
- Paclobutrazol Impurity 2 (CAS 66346-05-2)
- 4-azaspiro[2.5]octane-5,7-dione (CAS 1105663-34-0)
- 1-Cyclohexyl-N-(2-ethoxyethyl)ethan-1-amine (CAS 1157204-63-1)
- 5-Bromo-2-fluoroaniline (CAS 2924-09-6)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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