Eltrombopag Impurity 36 CAS 33696-00-3
| CAS No. | 33696-00-3 |
| Molecular Formula | C7H6BrNO3 |
| Molecular Weight | 232.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Eltrombopag Impurity 36 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Eltrombopag Impurity 36 (CAS 33696-00-3, C7H6BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Eltrombopag Impurity 36 (C7H6BrNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H6BrNO3 |
| Molecular Weight | 232.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 32 (CAS 98775-19-0)
- Eltrombopag Impurity 38 (CAS 500298-30-6)
- Eltrombopag Impurity 39 (CAS 103966-66-1)
- Eltrombopag Impurity 56 (CAS CATO-C4X-119856)
- Eltrombopag Impurity 83 (CAS CATO-C4X-119883)
- Eltrombopag Impurity 84 (CAS CATO-C4X-119884)
- Eltrombopag Impurity 85(E-Isomer) (CAS CATO-C4X-119885)
- Eltrombopag Impurity 9 (CAS CATO-C4X-11989)
Recommended Standards
- Methyl 6-bromo-3-hydroxypyridine-2-carboxylate (CAS 321601-48-3)
- Methyl 5-bromo-6-hydroxynicotinate (CAS 381247-99-0)
- 2-Bromo-3-nitrobenzyl alcohol (CAS 90407-20-8)
- Methyl 5-Bromo-2-hydroxyisonicotinate (CAS 913836-17-6)
- Glumetinib Impurity 11 (CAS CATO-C4X-325911)
- Vonoprazan Fumarate Impurity 118 (CAS CATO-C4X-1020118)
- Prilocaine EP Impurity F HCl (CAS 13327-14-5)
- (4-Chloro-2-fluoro-5-methylphenyl)(methyl)sulfane (CAS 1805954-46-4)
- 6-Methyl-1H-pyrrolo[3,2-b]pyridin-5-amine (CAS 2891455-69-7)
- 5,5,6,6-Tetrachlorodecane (CAS 91087-09-1)
- (S)-1-(2-fluorophenyl)-N-((S)-1-phenylethyl)ethan-1-amine phthalate (CAS 1428344-88-0)
- Dalbavancin Impurity 54 (CAS CATO-C4X-160254)
- 6-Chloro-2-(3-chloropropyl)quinazoline (CAS 2006277-48-9)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com