Ramipril EP Impurity H Oxalate CAS 104195-90-6
| CAS No. | 104195-90-6 |
| Molecular Formula | C23H32N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ramipril EP Impurity H Oxalate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ramipril EP Impurity H Oxalate (CAS 104195-90-6) is a certified pharmaceutical impurity reference standard with the molecular formula C23H32N2O5C2H2O4 and a molecular weight of 506.55 g/mol.
Ramipril EP Impurity H Oxalate (C23H32N2O5C2H2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ramipril EP Impurity H Oxalate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H32N2O5 C2H2O4 |
| Molecular Weight | 506.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Ramipril Standards
- Ramipril EP Impurity A (CAS 108313-11-7)
- Ramipril EP Impurity D (CAS 108731-95-9)
- Ramipril EP Impurity K (CAS 108736-10-3)
- Ramipril-d5 (CAS 1132661-86-9)
- Ramipril Impurity 4 (CAS 122076-80-6)
- Ramipril EP Impurity J (CAS 1246253-05-3)
- Ramipril EP Impurity N (CAS 129939-63-5)
- Ramipril EP Impurity I (CAS 129939-65-7)
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