Ramipril EP Impurity D CAS 108731-95-9
| CAS No. | 108731-95-9 |
| Molecular Formula | C23H30N2O4 |
| Molecular Weight | 398.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 398.50 g/mol gives Ramipril EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ramipril EP Impurity D (CAS 108731-95-9), a pharmacopoeial impurity reference standard (molecular formula C23H30N2O4, MW 398.50 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ramipril EP Impurity D (C23H30N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ramipril EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H30N2O4 |
| Molecular Weight | 398.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Ramipril Standards
- Ramipril EP Impurity A (CAS 108313-11-7)
- Ramipril EP Impurity E (CAS 87269-97-4)
- Ramipril EP Impurity L (CAS 1309040-96-7)
- Ramipril EP Impurity L(mixture) (CAS CATO-C4X-174412)
- Ramipril Impurity 1 (CAS CATO-C4X-17441)
- Ramipril (CAS 87333-19-5)
- Ramipril Impurity 27 (CAS 753405-33-3)
- Ramipril EP Impurity I (CAS 129939-65-7)
Recommended Standards
- Fesoterodine Impurity 7 (CAS CATO-C4X-16447)
- Teneligliptin impurity 38 (CAS CATO-C4X-176038)
- Promethazine Impurity 54 (CAS CATO-C4X-141854)
- Limaprost Impurity 12 (CAS CATO-C4X-214512)
- Cholecalciferol Impurity 19 (CAS CATO-C4X-158619)
- Valsartan Impurity 14 (CAS 137863-90-2)
- Rivaroxaban impurity 197 (CAS CATO-C4X-1090197)
- Methyl 2-bromo-5-methylthiazole-4-carboxylate (CAS 56355-61-4)
- 4-(2,3-Dimethylphenyl)-5-((4-ethylphenoxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 917748-23-3)
- 1-((3-Ethyl-1-methyl-1h-1,2,4-triazol-5-yl)methyl)-1h-pyrazol-4-amine (CAS 1342421-75-3)
- 3-Methyl-1-(4-(trifluoromethyl)benzyl)-1h-pyrazol-5-amine (CAS 1307705-43-6)
- Methyl 3-(5-methyl-1-phenyl-1H-pyrazole-4-carboxamido)thiophene-2-carboxylate (CAS 321574-08-7)
- 6-Bromo-2,2-difluorobenzo[d][1,3]dioxole-5-carboxylic acid (CAS 2451905-09-0)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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