Acebutolol EP Impurity B Hydrochloride CAS 73899-76-0
| CAS No. | 73899-76-0 |
| Molecular Formula | C16H24N2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Acebutolol EP Impurity B Hydrochloride.
CATO supplies Acebutolol EP Impurity B Hydrochloride (CAS 73899-76-0), a certified reference material (molecular formula C16H24N2O4HCl, MW 344.84 g/mol) for analytical method development and quality control.
The molecular framework of Acebutolol EP Impurity B Hydrochloride (C16H24N2O4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Acebutolol EP Impurity B Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H24N2O4 HCl |
| Molecular Weight | 344.84 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Acebutolol Standards
- Acebutolol Impurity 16 (CAS 1180584-47-7)
- Acebutolol-d5 (CAS 1189500-68-2)
- Acebutolol Hydrochloride - Impurity H (Freebase) (CAS 1329613-31-1)
- Acebutolol EP Impurity G (CAS 1330165-98-4)
- Acebutolol EP Impurity E (CAS 1432053-72-9)
- Acebutolol EP Impurity B (CAS 22568-64-5)
- Acebutolol Hydrochloride - Impurity E (Freebase) (CAS 27783-53-5)
- Acebutolol EP Impurity J (CAS 28197-36-6)
Recommended Standards
- (R)-3-(Boc-amino)-2-oxopiperidine (CAS 221874-51-7)
- 5-Iodo-6-(trifluoromethyl)pyridin-2-ol (CAS 1227515-14-1)
- tert-Butyl 3-bromo-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate (CAS 1000577-81-0)
- 3-((1H-pyrazol-1-yl)methyl)-4-isopropoxybenzaldehyde (CAS 1015844-32-2)
- Reactive Blue 19 (CAS 2580-78-1)
- N-(2-Ethylphenyl)-2-((3-oxo-4-(p-tolyl)-3,4-dihydropyrazin-2-yl)thio)acetamide (CAS 941935-24-6)
- Fmoc-[D??]Leu-OH (CAS 1190594-22-9)
- 2-Chloro-5-(2,5-difluorobenzoyl)pyridine (CAS 1187165-19-0)
- Tramadol EP Impurity E HCl (CAS 42036-65-7)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com