Tacrolimus Impurity 27 CAS 104987-25-9
| CAS No. | 104987-25-9 |
| Molecular Formula | C50H83NO12Si |
| Molecular Weight | 918.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tacrolimus Impurity 27 (CAS 104987-25-9), a pharmacopoeial impurity reference standard (molecular formula C50H83NO12Si, MW 918.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C50H83NO12Si, Tacrolimus Impurity 27 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 918.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tacrolimus Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C50H83NO12Si |
| Molecular Weight | 918.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus Impurity 40 (CAS CATO-C4X-130040)
- Tacrolimus Impurity 41 (CAS CATO-C4X-130041)
- Tacrolimus Impurity 42 (CAS CATO-C4X-130042)
- Tacrolimus impurity 49 (CAS CATO-C4X-130049)
- Tacrolimus impurity 50 (CAS CATO-C4X-130050)
- Tacrolimus Hydroxy Acid Impurity (CAS 1700657-83-5)
- Tacrolimus 21-Carboxy Acid (CAS CATO-C4X-130029)
- Tacrolimus impurity 65 (CAS CATO-C4X-130065)
Recommended Standards
- Aprocitentan impurity 3 (CAS CATO-C4X-33553)
- 2,5-Bis((3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)oxy)terephthalohydrazide (CAS 2569674-66-2)
- (Sar1,Ile4ยท8)-Angiotensin II (CAS 185461-45-4)
- NDI12-4Br (CAS 2086725-21-3)
- Olmesartan Impurity 34 (CAS 116857-04-6)
- Neostigmine impurity 44 (CAS CATO-C4X-204244)
- Atenolol EP Impurity E (CAS 141650-31-9)
- (S)-3-(2-chloropyrimidin-4-yl)-4-isopropyloxazolidin-2-one (CAS 1429180-81-3)
- 5-Bromo-N-methylpyridine-3-sulfonamide (CAS 173999-19-4)
- (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine (S)-|A,|A-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether (S)-|A,|A-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether 848821-61-4 (CAS 848821-61-4)
- N-(2-Guanidinoethyl)isoquinoline-5-sulfonamide (CAS 91742-10-8)
- 2-(2-Methyl-1h-indol-3-yl)-N-(pyridin-2-ylmethyl)ethan-1-amine dihydrochloride (CAS 1049786-08-4)
- (3-Aminopropyl)(2-methoxyethyl)methylamine (CAS 74247-25-9)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com