Tacrolimus Hydroxy Acid Impurity CAS 1700657-83-5
| CAS No. | 1700657-83-5 |
| Molecular Formula | C44H71NO13 |
| Molecular Weight | 822.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tacrolimus Hydroxy Acid Impurity (C44H71NO13) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tacrolimus Hydroxy Acid Impurity (CAS 1700657-83-5) is a certified pharmaceutical impurity reference standard with the molecular formula C44H71NO13 and a molecular weight of 822.03 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tacrolimus Hydroxy Acid Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H71NO13 |
| Molecular Weight | 822.03 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus 21-Carboxy Acid (CAS CATO-C4X-130029)
- Tacrolimus impurity 65 (CAS CATO-C4X-130065)
- Tacrolimus impurity 69 (CAS CATO-C4X-130069)
- Tacrolimus impurity 70 (CAS CATO-C4X-130070)
- Tacrolimus impurity 66 (CAS CATO-C4X-130066)
- Tacrolimus impurity 62 (CAS CATO-C4X-130062)
- Tacrolimus Methyl Ether (CAS 124554-16-1)
- Tacrolimus Impurity 39 (CAS CATO-C4X-130039)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com