Dolutegravir Sodium Salt CAS 1051375-19-9
| CAS No. | 1051375-19-9 |
| Molecular Formula | C20H18F2N3O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dolutegravir Sodium Salt.
CATO supplies Dolutegravir Sodium Salt (CAS 1051375-19-9), a certified reference material (molecular formula C20H18F2N3O5Na, MW 441.37 g/mol) for analytical method development and quality control.
Structurally, Dolutegravir Sodium Salt (C20H18F2N3O5Na) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.5, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 441.37 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Dolutegravir Sodium Salt under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18F2N3O5 Na |
| Molecular Weight | 441.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dolutegravir Standards
- Dolutegravir (CAS 1051375-16-6)
- Dolutegravir Impurity 22 (CAS 1206102-11-5)
- Dolutegravir Sodium Monohydrate - API Standards (CAS 1229006-39-6)
- Dolutegravir Impurity N13 (CAS 1246616-73-8)
- Dolutegravir Impurity 14 (CAS 127958-23-0)
- Dolutegravir Impurity 2 (CAS 1309560-49-3)
- Dolutegravir Impurity 27 (CAS 1335210-31-5)
- Dolutegravir Impurity N1 (CAS 1335210-34-8)
Recommended Standards
- 1,3-Bis(3-methoxyphenyl)propan-1-one (CAS 898774-46-4)
- 3,5-Dichloro-4-(difluoromethoxy)benzodifluoride (CAS 1806296-77-4)
- 2-({[(5-chloro-1,2,3-thiadiazol-4-yl)methoxy]amino}methylidene)-5-(4-chlorophenyl)cyclohexane-1,3-dione (CAS 1192655-41-6)
- Methyl 4-oxo-1-(p-tolyl)-1,4-dihydropyridazine-3-carboxylate (CAS 478063-54-6)
- 2-(1-chloroethyl)pyrimidin-4-amine (CAS 1502651-24-2)
- 4-Amino-2-chloro-3-fluorobenzoic acid (CAS 1124214-25-0)
- N-(benzo[d][1,3]dioxol-5-ylmethyl)-3-ethoxypropan-1-amine (CAS 774551-36-9)
- N-(4-Ethoxyphenyl)-2,2-diphenylacetamide (CAS 23105-48-8)
- 7-Isopropylindoline (CAS 954571-03-0)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com