Atrasentan Impurity 91 CAS 1059043-44-5
| CAS No. | 1059043-44-5 |
| Molecular Formula | C34H48N2O6 |
| Molecular Weight | 580.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Atrasentan Impurity 91 (C34H48N2O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Atrasentan Impurity 91 (CAS 1059043-44-5) is a certified pharmaceutical impurity reference standard with the molecular formula C34H48N2O6 and a molecular weight of 580.77 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Atrasentan Impurity 91 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H48N2O6 |
| Molecular Weight | 580.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 105 (CAS 1059052-12-8)
- Atrasentan Impurity 114 (CAS 1073746-06-1)
- Atrasentan Impurity 133 (CAS 1058349-06-6)
- Atrasentan Impurity 137 (CAS 1058349-12-4)
- Atrasentan Impurity 139 (CAS 1058349-18-0)
- Atrasentan Impurity 143 (CAS 1058349-56-6)
- Atrasentan Impurity 145 (CAS 1058350-11-0)
- Atrasentan Impurity 148 (CAS 1058350-27-8)
Recommended Standards
- Atrasentan Impurity 73 (CAS 1058404-70-8)
- 5,5′-[2,5-Bis(2-ethylhexyl)-2,3,5,6-tetrahydro-3,6-dioxopyrrolo[3,4-c]pyrrole-1,4-diyl]bis[2-thiophenecarboxaldehyde] (CAS 1239218-96-2)
- Atrasentan Impurity 52 (CAS 1059057-00-9)
- Valnemulin EP Impurity A (Mixture of Diastereomers) (CAS 1624614-06-7)
- Olmesartan Impurity 114 (CAS CATO-C4X-1097114)
- Bicalutamide EP Impurity H (CAS 2512198-58-0)
- Sugammadex Impurity 26 (CAS CATO-C4X-190626)
- 3-(4-Nitro-phenyl)-isoxazole-5-carboxylic acid ethyl ester (CAS 370848-42-3)
- 3-(2-Acetyl-1,2-dihydroisoquinolin-1-yl)pentane-2,4-dione (CAS 94129-35-8)
- 1-Benzyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide (CAS 338755-06-9)
- Everolimus Impurity 21 (CAS 143030-02-8)
- 1',2,3,4',5,6-Hexahydro-2'H-spiro[pyran-4,3'-quinoline] (CAS 1448855-03-5)
- 1,3-Diethyl 2-(3-methylphenyl)propanedioate (CAS 94112-78-4)
- Neuropeptide Y (2-36) (human, rat) trifluoroacetate salt (CAS 123139-39-9)
Why CATO?
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