Clotrimazole Impurity 13 CAS 108-41-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.108-41-8
Molecular FormulaC7H7Cl
Molecular Weight126.58 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Clotrimazole Impurity 13 CAS 108-41-8 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO supplies Clotrimazole Impurity 13 (CAS 108-41-8), a pharmacopoeial impurity reference standard (molecular formula C7H7Cl, MW 126.58 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to chlorine substitution, an aromatic ring system, Clotrimazole Impurity 13 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 126.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H7Cl
Molecular Weight126.58 g/mol
Purity>95%
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing

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