Betamethasone Impurity 135 CAS CATO-C4X-1437135
| CAS No. | CATO-C4X-1437135 |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Betamethasone Impurity 135 (CAS CATO-C4X-1437135), a pharmacopoeial impurity reference standard (molecular formula C22H30FO8P, MW 472.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution, Betamethasone Impurity 135 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 472.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone impurity 103 (CAS CATO-C4X-1437103)
- Betamethasone Impurity 132 (CAS CATO-C4X-1437132)
- Betamethasone impurity 45 (CAS 1215899-29-8)
- Betamethasone impurity 55 (CAS 1202002-02-5)
- Betamethasone impurity 56 (CAS 1202002-00-3)
- Betamethasone impurity 96 (CAS CATO-C4X-143796)
- Betamethasone Unknown Impurity 3 (CAS CATO-CPS-2303001)
- Betamethasone Acetate EP Impurity C (CAS 330157-05-6)
Recommended Standards
- Dexamethasone impurity 65 (CAS 1202002-01-4)
- Dexamethasone impurity 64 (CAS CATO-C4X-116564)
- Dexamethasone impurity 63 (CAS 1202001-99-7)
- D-Homo B Derivative of Dexamethasone (CAS CATO-C4X-116552)
- Milrinone Impurity 35 (CAS 52600-51-8)
- Paclitaxel EP Impurity A (CAS 173101-54-7)
- Vinpocetine Impurity 39 (CAS 27773-39-3)
- 4-Amino-5-chloro-6-ethoxypicolinic acid (CAS 904311-15-5)
- Methyl 3-fluoro-4-(3-methoxyphenyl)benzoate (CAS 1820707-58-1)
- 1-[3-(Morpholin-4-yl)phenyl]ethan-1-amine (CAS 477312-45-1)
- 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine (CAS 866049-86-7)
- (1-(1-(Methylamino)ethyl)cyclobutyl)methanol (CAS 1890934-79-8)
- Z-Arg-Arg-4MβNA (CAS 73167-98-3)
- D-β-Asp15-Tirzepatide (CAS CATO-CPTD788930)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com