Clotrimazole Impurity 26 CAS 29921-41-3
| CAS No. | 29921-41-3 |
| Molecular Formula | C13H11Cl |
| Molecular Weight | 202.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Clotrimazole Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Clotrimazole Impurity 26 (CAS 29921-41-3), a pharmacopoeial impurity reference standard (molecular formula C13H11Cl, MW 202.68 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Clotrimazole Impurity 26 (C13H11Cl) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H11Cl |
| Molecular Weight | 202.68 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
Related Clotrimazole Standards
- Clotrimazole Impurity 12 (CAS 15145-69-4)
- Clotrimazole EP Impurity E (CAS 5162-03-8)
- Clotrimazole Impurity 20 (CAS 3005-50-3)
- Clotrimazole Impurity 15 (CAS 2136-81-4)
- Clotrimazole Impurity 11 (CAS 611-19-8)
- Clotrimazole Impurity 25 (CAS 3509-85-1)
- Clotrimazole Impurity 27 (CAS 56153-60-7)
- Clotrimazole Impurity 13 (CAS 108-41-8)
Recommended Standards
- 2-Quinoxalinecarbonyl chloride 54745-92-5 quinoxaline-2-carbonyl chloride (CAS 54745-92-5)
- Benzhydryl Chloride (CAS 90-99-3)
- p-Chlorobenzylbenzene (CAS 831-81-2)
- 4-Phenylbenzyl chloride (CAS 1667-11-4)
- Atosiban Impurity 59 (CAS CATO-C4X-229359)
- Amikacin EP Impurity I (CAS 40371-51-5)
- Dapoxetine Impurity 46 (CAS 524-42-5)
- 4-(2,6-Difluorophenyl)butan-2-ol (CAS 1342201-64-2)
- 2-(3-Chloro-4-fluorophenyl)piperidine (CAS 901921-07-1)
- Fmoc-Ser-OMe (CAS 82911-78-2)
- Methyl 3-(((3-(trifluoromethyl)phenyl)thio)methyl)benzoate (CAS 650617-47-3)
- N-(2-Fluoro-3-(hydroxymethyl)phenyl)acetamide (CAS 1003707-72-9)
- (S)-DM-SEGPHOS (CAS 210169-57-6)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
Why CATO?
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