Promethazine Impurity 54 CAS CATO-C4X-141854
| CAS No. | CATO-C4X-141854 |
| Molecular Formula | C17H22N2O5S2 |
| Molecular Weight | 398.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Promethazine Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Promethazine Impurity 54 (CAS CATO-C4X-141854, C17H22N2O5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C17H22N2O5S2, Promethazine Impurity 54 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 398.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H22N2O5S2 |
| Molecular Weight | 398.50 g/mol |
| Purity | ＞95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Promethazine Standards
- Promethazine Impurity 46 (CAS CATO-C4X-141846)
- Promethazine Impurity 50 (CAS CATO-C4X-141850)
- Promethazine N-β-D-Glucuronide (CAS 137908-81-7)
- Promethazine Impurity 47 (CAS CATO-C4X-141847)
- Promethazine Impurity 66 (CAS CATO-C4X-141866)
- Promethazine Impurity 67 (CAS 7647-63-4)
- Promethazine Impurity 49 (CAS CATO-C4X-141849)
- Promethazine Impurity 37 (CAS CATO-C4X-141837)
Recommended Standards
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- Fosfomycin Impurity 72 (CAS 26017-01-6)
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