Loxoprofen Impurity 50 CAS 111128-12-2
| CAS No. | 111128-12-2 |
| Molecular Formula | C10H11BrO2 |
| Molecular Weight | 243.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Loxoprofen Impurity 50 (CAS 111128-12-2, C10H11BrO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, Loxoprofen Impurity 50 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Loxoprofen Impurity 50 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11BrO2 |
| Molecular Weight | 243.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
Related Loxoprofen Standards
- Loxoprofen impurity 103 (CAS CATO-C4X-1488103)
- Loxoprofen Impurity 67 (CAS 32454-35-6)
- Loxoprofen Impurity 71 (CAS CATO-C4X-148871)
- Loxoprofen impurity 118 (CAS CATO-C4X-1488118)
- Loxoprofen impurity 119 (CAS CATO-C4X-1488119)
- Loxoprofen Impurity 147 (CAS CATO-C4X-1488147)
- Loxoprofen Impurity 148 (CAS CATO-C4X-1488148)
- Loxoprofen Impurity 154 (CAS 90319-74-7)
Recommended Standards
- LoxLoxoprofen Impurity 63 (CAS 2172861-70-8)
- 7-bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine (CAS 1431546-98-3)
- Ethyl 2-bromophenylacetate (CAS 2178-24-7)
- Apalutamide Impurity 38 (CAS CATO-C4X-274938)
- Eravacycline Impurity 12(TP-5799） (CAS CATO-C4X-293812)
- Diazepam EP Impurity C (CAS 5220-02-0)
- Finerenone Impurity 190 (CAS CATO-C4X-2880190)
- 5-((Octyloxy)methyl)quinolin-8-ol (CAS 102269-68-1)
- (R)-tert-Butyl 3-((6-methylpyridazin-3-yl)oxy)pyrrolidine-1-carboxylate (CAS 1264035-38-2)
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- 1-Cyclopropanecarbonylazetidin-3-ol (CAS 1339451-70-5)
- Pyflubumide (CAS 926914-55-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com