Apalutamide Impurity 38 CAS CATO-C4X-274938
| CAS No. | CATO-C4X-274938 |
| Molecular Formula | C9H11BrN2O |
| Molecular Weight | 243.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apalutamide Impurity 38 (CAS CATO-C4X-274938) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11BrN2O and a molecular weight of 243.10 g/mol.
Structurally, Apalutamide Impurity 38 (C9H11BrN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 243.10 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Apalutamide Impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11BrN2O |
| Molecular Weight | 243.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Apalutamide Standards
- Apalutamide impurity 88 (CAS 1367708-38-0)
- Apalutamide Impurity 34 (CAS CATO-C4X-274934)
- Apalutamide Impurity 66 (CAS CATO-C4X-274966)
- Apalutamide Impurity 12 (CAS 2422147-84-8)
- Apalutamide Impurity 15 (CAS 915087-26-2)
- Apalutamide Impurity 62 (CAS CATO-C4X-274962)
- Apalutamide Impurity 24 (CAS CATO-C4X-274924)
- Apalutamide Impurity 71 (CAS CATO-C4X-274971)
Recommended Standards
- Loxoprofen Impurity 67 (CAS 32454-35-6)
- 2-Amino-5-bromo-N,3-dimethylbenzamide (CAS 890707-30-9)
- LoxLoxoprofen Impurity 63 (CAS 2172861-70-8)
- Bromuron (CAS 3408-97-7)
- Nebivolol Impurity 72 (CAS CATO-C4X-196872)
- Neratinib Impurity 6 (CAS CATO-C4X-11346)
- Nicardipine Impurity N1 (CAS 10323-98-5)
- 3-methyl-1H-pyrazole-4-carboxylic acid 3-methyl-2H-pyrazole-4-carboxylic acid 40704-11-8 (CAS 40704-11-8)
- 2-(3-(4-Fluorophenyl)oxetan-3-yl)acetic acid (CAS 1903709-22-7)
- 3-Ethoxysalicylaldehyde (CAS 492-88-6)
- JWH-018 5-Hydroxypentyl metabolite (CAS 335161-21-2)
- 7-Bromo-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1245708-33-1)
- 3,6-Dimethyl-5-nitropyridin-2-ol (CAS 57179-69-8)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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