Amlodipine Impurity 134 CAS CATO-C4X-1095134
| CAS No. | CATO-C4X-1095134 |
| Molecular Formula | C15H17ClO4 |
| Molecular Weight | 296.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Amlodipine Impurity 134 (CAS CATO-C4X-1095134, C15H17ClO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Amlodipine Impurity 134 (C15H17ClO4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 296.75 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Amlodipine Impurity 134 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17ClO4 |
| Molecular Weight | 296.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Amlodipine Standards
- Amlodipine Impurity 79 (CAS 3516-73-2)
- Amlodipine Impurity N13 (CAS 70677-78-0)
- Amlodipine Impurity N2 (CAS 111429-90-4)
- Amlodipine impurity 124 (CAS CATO-C4X-1095124)
- Amlodipine Impurity 114 (CAS CATO-C4X-1095114)
- Amlodipine Impurity 77 (CAS 265136-65-0)
- Amlodipine Impurity 27 (CAS 88150-75-8)
- Amlodipine Impurity 156 (CAS CATO-C4X-1095156)
Recommended Standards
- 3,5-Bis(methylsulfonyl)benzoyl chloride 3,5-bis(methylsulphonyl)benzoyl chloride 90649-99-3 (CAS 90649-99-3)
- Enalapril Impurity 10 (CAS 32315-10-9)
- 677737-58-5 1-{[(4-Chlorophenyl)methylidene]amino}-4-phenyl-1H-imidazol-2-amine DTXSID90636034 (CAS 677737-58-5)
- 2-[4-(trifluoromethyl)phenyl]benzoyl chloride (CAS 180340-74-3)
- Nintedanib Impurity 11 (CAS CATO-C4X-181411)
- Orforglipron impurity 20 (CAS CATO-C4X-323420)
- Avibactam impurity 92 (CAS CATO-C4X-134892)
- 5-phenoxypyrimidin-2-amine (CAS 99185-52-1)
- N-[(1,1-Dimethylethoxy)carbonyl]-3-[[(2-propen-1-yloxy)carbonyl]amino]-L-alanine (CAS 161561-83-7)
- tert-Butyl (2R,4S)-2-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 1627972-84-2)
- Upadacitinib Impurity 199 (CAS CATO-C4X-2405199)
- 2-Hydroxy-6-phenylhexanenitrile (CAS 288863-28-5)
- 3-[4-(difluoromethoxy)phenyl]-3-oxopropanenitrile (CAS 1017036-63-3)
- Peptide-GMF (CAS CATO-CPTD788469)
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