Amlodipine Impurity 114 CAS CATO-C4X-1095114
| CAS No. | CATO-C4X-1095114 |
| Molecular Formula | C12H16Cl2O5 |
| Molecular Weight | 311.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Amlodipine Impurity 114 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Amlodipine Impurity 114 (CAS CATO-C4X-1095114), a pharmacopoeial impurity reference standard (molecular formula C12H16Cl2O5, MW 311.16 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Amlodipine Impurity 114 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16Cl2O5 |
| Molecular Weight | 311.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Amlodipine Standards
- Amlodipine Impurity N2 (CAS 111429-90-4)
- Amlodipine Impurity 77 (CAS 265136-65-0)
- Amlodipine Impurity 27 (CAS 88150-75-8)
- Amlodipine Impurity 156 (CAS CATO-C4X-1095156)
- Amlodipine Impurity N13 (CAS 70677-78-0)
- Amlodipine Impurity 48 (CAS CATO-C4X-109548)
- Amlodipine Impurity 79 (CAS 3516-73-2)
- Amlodipine Impurity 134 (CAS CATO-C4X-1095134)
Recommended Standards
- tert-butyl 3-iodopiperidine-1-carboxylate (CAS 850761-36-3)
- Indometacin Impurity 50 (CAS CATO-C4X-147050)
- tert-butyl 3-(iodomethyl)pyrrolidine-1-carboxylate (CAS 479622-36-1)
- Indometacin Impurity 51 (CAS CATO-C4X-147051)
- Atosiban Impurity 103 (CAS CATO-C4X-2293103)
- Budesonide Impurity 35 (CAS 3079028-41-1)
- Landiolol Impurity 7 (CAS 190601-22-0)
- N,N-Dimethyl-4-(4-nitrophenoxy)-6-(trifluoromethyl)pyrimidin-2-amine (CAS 338792-45-3)
- N'-benzoyl-5-(((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazole-3-carbohydrazide (CAS 321432-36-4)
- (2-Chloroethyl)trimethylsilane (CAS 17336-78-6)
- Benzoylmesaconine-7-Palmitate (CAS 158584-86-2)
- 4-(Piperazin-1-yl)benzoic acid hydrochloride (CAS 1094033-66-5)
- 1-Methyl-N-(tetrahydro-2H-pyran-4-yl)piperidin-4-amine dihydrochloride (CAS 1187930-33-1)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com