Benazepril EP Impurity D CAS 112110-48-2
| CAS No. | 112110-48-2 |
| Molecular Formula | C24H34N2O5 |
| Molecular Weight | 430.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benazepril EP Impurity D.
As a process- or degradation-related impurity, Benazepril EP Impurity D (CAS 112110-48-2, C24H34N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Benazepril EP Impurity D (C24H34N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 430.54 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H34N2O5 |
| Molecular Weight | 430.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Benazepril Standards
- Benazepril-d5 (CAS 1279200-03-1)
- Benazepril EP Impurity A (CAS 131064-75-0)
- Benazepril EP Impurity B(1R,3S-Isomer) (CAS 86541-76-6)
- Benazepril Impurity B (CAS 98626-50-7)
- Benazepril (CAS 86541-75-5)
- Benazepril Impurity 13 (CAS CATO-C4X-209613)
- Benazepril EP Impurity C (CAS 86541-78-8)
- Benazepril tert-Butyl Ester (CAS 109010-61-9)
Recommended Standards
- 3-((4-Methoxy-N-methylphenyl)sulfonamido)-N-(4-methylbenzyl)thiophene-2-carboxamide (CAS 1115871-62-9)
- Triethyl 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate (CAS 114873-52-8)
- Ingenol Mebutate (CAS 75567-37-2)
- (3,5-Dimethyl-1H-pyrazol-1-yl)(3-((4-phenylpiperazin-1-yl)sulfonyl)thiophen-2-yl)methanone (CAS 1171238-68-8)
- Rabeprazole Impurity 22 (CAS 675198-19-3)
- Ibuprofen Impurity 74 (CAS 1261642-35-6)
- Atrasentan Impurity 76 (CAS 1058551-13-5)
- (5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(2,4-dimethylphenyl)methanone (CAS 898779-19-6)
- N-(Furan-2-ylmethyl)-2-methyl-N-(2-(thiophen-2-yl)ethyl)benzamide (CAS 1396715-76-6)
- CAS 219957-04-7 (CAS 219957-04-7)
- 1-(pyrrolidin-3-yl)-1H-1,2,4-triazole (CAS 708204-49-3)
- NHQ37BJZ2Z 7785-23-1 Silver bromide Silver bromide (AgBr) EINECS 232-076-8 UNII-NHQ37BJZ2Z EC 232-076-8 (CAS 7785-23-1)
- 5-Phenyl-1H-1,2,4-triazole-3-sulfonyl chloride (CAS 1381947-50-7)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com