Benazepril EP Impurity B(1R,3S-Isomer) CAS 86541-76-6
| CAS No. | 86541-76-6 |
| Molecular Formula | C24H28N2O5 |
| Molecular Weight | 424.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Benazepril EP Impurity B(1R,3S-Isomer) (CAS 86541-76-6) is a certified pharmaceutical impurity reference standard with the molecular formula C24H28N2O5 and a molecular weight of 424.49 g/mol.
Based on its molecular formula C24H28N2O5, Benazepril EP Impurity B(1R,3S-Isomer) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 424.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H28N2O5 |
| Molecular Weight | 424.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Related Benazepril Standards
- Benazepril EP Impurity A (CAS 131064-75-0)
- Benazepril Impurity B (CAS 98626-50-7)
- Benazepril (CAS 86541-75-5)
- Benazepril-d5 (CAS 1279200-03-1)
- Benazepril EP Impurity D (CAS 112110-48-2)
- Benazepril EP Impurity C (CAS 86541-78-8)
- Benazepril Impurity 13 (CAS CATO-C4X-209613)
- Benazepril tert-Butyl Ester (CAS 109010-61-9)
Recommended Standards
- Paliperidone Impurity 69 (CAS CATO-C4X-172469)
- Famotidine impurity 64 (CAS CATO-C4X-139264)
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- Mianserin Impurity 87 (CAS CATO-C4X-136987)
- Orforglipron Impurity 55 (CAS 2212021-93-5)
- Nalmefene Impurity 15 (CAS CATO-C4X-126815)
- Rivaroxaban Impurity N8 (CAS 1770812-38-8)
- 2-Amino-N,N-dimethylpropane-1-sulfonamide (CAS 1225970-29-5)
- 5-Chloro-2-fluorophenylacetic Acid (CAS 261762-97-4)
- 2-Cyclopropyl-2-methylpropan-1-amine (CAS 1315060-27-5)
- 3,4-Difluoro-5-hydroxybenzoic acid (CAS 749230-45-3)
- Ethyl 2-(2-(4-phenylpiperazin-1-yl)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 833439-05-7)
- 1-((5-Chloro-4-methoxypyridin-3-yl)sulfonyl)piperazine (CAS 1352540-69-2)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
Why CATO?
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