Calcipotriol EP Impurity D CAS 112827-99-3
| CAS No. | 112827-99-3 |
| Molecular Formula | C27H40O3 |
| Molecular Weight | 412.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Calcipotriol EP Impurity D (C27H40O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Calcipotriol EP Impurity D (CAS 112827-99-3), a pharmacopoeial impurity reference standard (molecular formula C27H40O3, MW 412.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Calcipotriol EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H40O3 |
| Molecular Weight | 412.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Calcipotriol Standards
- Calcipotriol (CAS 112828-00-9)
- Calcipotriol Impurity A (CAS 126860-84-2)
- Calcipotriol Impurity 13 (CAS 112849-47-5)
- Calcipotriol EP Impurity B (CAS 2948288-30-8)
- Calcipotriol Impurity 25 (CAS CATO-C4X-122225)
- Calcipotriol EP Impurity C (CAS 113082-99-8)
- Calcipotriol (CAS 112965-21-6)
- Calcipotriol Impurity 41 (CAS CATO-C4X-122241)
Recommended Standards
- Calcipotriol Impurity 43 (CAS 176302-02-6)
- Calcipotriol EP Impurity I (CAS CATO-C4X-12229)
- Progesterone Impurity 68 (CAS CATO-C4X-150268)
- Calcitriol Impurity 59 (CAS 934338-44-0)
- Palbociclib Impurity 64 (CAS CATO-C4X-112564)
- Lumateperone Impurity 56 (CAS CATO-C4X-220156)
- Olanzapine Impurity 62 (CAS 17842-18-1)
- n-(Naphthalen-2-yl)cyclopentanecarboxamide (CAS 540754-74-3)
- Methyl 1H-indole-3-carboximidoate hydrochloride (CAS 74862-25-2)
- Cefdinir dimer (CAS CATO-C4X-121050)
- (1-(Cyclobutylmethyl)-1H-pyrazol-4-yl)methanamine (CAS 1483049-01-9)
- (3R)-4-(Benzyloxy)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid (CAS 1233495-08-3)
- 5-Iodo-7-(trifluoromethyl)indoline-2,3-dione (CAS 1067187-88-5)
- Semaglutide Impurity 144 (CAS 394210-59-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com