Calcipotriol Impurity 43 CAS 176302-02-6
| CAS No. | 176302-02-6 |
| Molecular Formula | C27H40O3 |
| Molecular Weight | 412.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 412.60 g/mol gives Calcipotriol Impurity 43 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Calcipotriol Impurity 43 (CAS 176302-02-6) is a certified pharmaceutical impurity reference standard with the molecular formula C27H40O3 and a molecular weight of 412.60 g/mol.
The molecular framework of Calcipotriol Impurity 43 (C27H40O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Calcipotriol Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H40O3 |
| Molecular Weight | 412.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
Related Calcipotriol Standards
- Calcipotriol (CAS 112828-00-9)
- Calcipotriol Impurity A (CAS 126860-84-2)
- Calcipotriol Impurity 13 (CAS 112849-47-5)
- Calcipotriol EP Impurity B (CAS 2948288-30-8)
- Calcipotriol Impurity 25 (CAS CATO-C4X-122225)
- Calcipotriol EP Impurity C (CAS 113082-99-8)
- Calcipotriol (CAS 112965-21-6)
- Calcipotriol EP Impurity D (CAS 112827-99-3)
Recommended Standards
- Calcipotriol Impurity 41 (CAS CATO-C4X-122241)
- Calcipotriol EP Impurity I (CAS CATO-C4X-12229)
- Progesterone Impurity 68 (CAS CATO-C4X-150268)
- Calcitriol Impurity 59 (CAS 934338-44-0)
- Benzylpenicillin Potassium EP Impurity I potassium salt (CAS 31447-86-6)
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