Chlorpheniramine Maleate CAS 113-92-8
| CAS No. | 113-92-8 |
| Molecular Formula | C16H19ClN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Chlorpheniramine Maleate (C16H19ClN2C4H4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Chlorpheniramine Maleate (CAS 113-92-8) is a high-purity analytical reference standard with the molecular formula C16H19ClN2C4H4O4 and a molecular weight of 390.86 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN2 C4H4O4 |
| Molecular Weight | 390.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorpheniramine Standards
- Chlorpheniramine Impurity 41 (CAS 101286-08-2)
- Chlorpheniramine-d6 (CAS 1185054-60-7)
- Chlorpheniramine Impurity 15 (CAS 120244-82-8)
- Chlorpheniramine-d6 Maleate Salt (CAS 1219806-45-7)
- Chlorpheniramine (CAS 132-22-9)
- Chlorpheniramine Nitrile-d6 (CAS 1329488-38-1)
- R-Chlorpheniramine N-Oxide (CAS 142494-45-9)
- S-Chlorpheniramine N-0xide (CAS 142494-46-0)
Recommended Standards
- (R)-1-Amino-indan-4-ol hydrochloride (CAS 2097073-21-5)
- 2-(Perfluoropropyl)pyrimidin-5-amine (CAS 2108966-38-5)
- 2-(4-Hydroxypiperidin-1-yl)acetamide (CAS 116833-24-0)
- (2R,2'S)-rel-2,2'-Azanediyldisuccinic acid (CAS 131669-35-7)
- tert-Butyl 4-(2-fluoroethyl)piperidine-1-carboxylate (CAS 184042-54-4)
- Cyclohex-3-en-1-yl(3-(methylthio)-8-azabicyclo[3.2.1]octan-8-yl)methanone (CAS 1798460-54-4)
- Ledipasvir Impurity 51 (CAS CATO-C4X-331351)
- 52168-52-2 2-(~2~H_3_)Methyl-2-nitro(~2~H_6_)propane DTXSID50491429 (CAS 52168-52-2)
- [2S-[2α,3β(1R,2R)]]-4,8-Anhydro-1,3,7-trideoxy-7-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-L-talo-2-octulose (CAS 66262-70-2)
- Hexapeptide-9 (CAS 885024-94-2)
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