Sorafenib-d3 CAS 1130115-44-4
| CAS No. | 1130115-44-4 |
| Molecular Formula | - |
| Molecular Weight | 467.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sorafenib-d3 is closely related to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Sorafenib-d3 (CAS 1130115-44-4), molecular formula C21H13D3ClF3N4O3 and molecular weight 467.84 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Sorafenib-d3 (C21H13D3ClF3N4O3) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Sorafenib-d3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H13D3ClF3N4O3 |
| Molecular Weight | 467.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Sorafenib Standards
- Sorafenib Related Compound 28 (CAS 583840-04-4)
- Sorafenib related compound 26 (CAS 573673-43-5)
- Sorafenib (Base) (CAS 284461-73-0)
- Sorafenib Impurity 40 (CAS 1290546-48-3)
- Sorafenib Impurity 42 (CAS CATO-C4X-112442)
- Sorafenib EP Impurity H (CAS 1431697-81-2)
- Sorafenib Impurity 59 (CAS CATO-C4X-112459)
- Sorafenib Impurity 22 (CAS 583840-03-3)
Recommended Standards
- 2-(5-Chloro-1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazin-4-yl)-2-methyl-N-(3-(trifluoromethyl)phenyl)hydrazine-1-carboxamide (CAS 320421-74-7)
- Zomepirac acyl-β-D-glucuronide (CAS 75871-31-7)
- 1-((2-Chloro-5-(trifluoromethyl)phenyl)amino)-1-oxopropan-2-yl 3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanoate (CAS 875325-38-5)
- 2-[[4-[(5S)-5-[[[(5- Chloro- 2- thienyl)carbonyl]amino]methyl] -2-oxo-3-oxazolidinyl] phenyl](2-hydroxyethyl)amino]-2-oxo-acetic Acid (CAS 1160169-98-1)
- 3-(2-Methoxyphenyl)-1-(thiophen-2-yl)propan-1-one (CAS 685108-47-8)
- 1-(6-Bromo-3-pyridyl)cyclopropanamine (CAS 1060811-36-0)
- (R)-4-Isopropyl-2-(6-phenylpyridin-2-yl)-4,5-dihydrooxazole (CAS 2757082-65-6)
- 6-Ethoxybenzo[c][1,2]oxaborol-1(3H)-ol (CAS 1268390-29-9)
- 4-[(4-Chlorophenyl)sulfanyl]-6-(methanesulfonylmethyl)-2-methylpyrimidine (CAS 338967-62-7)
- n-Allyl-4-bromo-3,5-dimethoxybenzamide (CAS 923153-13-3)
- 6-Fluoro-3-iodo-2-methoxybenzaldehyde (CAS 1394291-39-4)
- 2-[4-(Carboxymethyl)phenyl]-2,2-difluoroacetic Acid (CAS 1436389-36-4)
- Cyclobenzaprine USP Related Compound A (CAS 18029-54-4)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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