Sorafenib Impurity 59 CAS CATO-C4X-112459
| CAS No. | CATO-C4X-112459 |
| Molecular Formula | C17H10Cl2F6N2O3 |
| Molecular Weight | 475.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sorafenib Impurity 59.
CATO supplies Sorafenib Impurity 59 (CAS CATO-C4X-112459), a pharmacopoeial impurity reference standard (molecular formula C17H10Cl2F6N2O3, MW 475.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Sorafenib Impurity 59 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 475.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sorafenib Impurity 59 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H10Cl2F6N2O3 |
| Molecular Weight | 475.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Sorafenib Standards
- Sorafenib Impurity 22 (CAS 583840-03-3)
- Sorafenib-d3 (CAS 1130115-44-4)
- Sorafenib Related Compound 28 (CAS 583840-04-4)
- Sorafenib related compound 26 (CAS 573673-43-5)
- Sorafenib (Base) (CAS 284461-73-0)
- Sorafenib Impurity 40 (CAS 1290546-48-3)
- Sorafenib Impurity 42 (CAS CATO-C4X-112442)
- Sorafenib EP Impurity H (CAS 1431697-81-2)
Recommended Standards
- 3-(2,4-Dichlorophenyl)-N-(3,4-dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 400075-14-1)
- 2’,3’-Dideoxyadenosine 5’-Triphosphate (CAS 24027-80-3)
- Resmetirom impurity 112 (CAS CATO-C4X-2912112)
- Delafloxacin Impurity 24 (CAS CATO-C4X-263724)
- Baloxavir Impurity 38 (CAS CATO-C4X-210838)
- Teneligliptin (2R,4R)-Isomer Impurity HBr (CAS 1404559-17-6(free base))
- N-Nitroso Etilefrine EP Impurity F (CAS 20689-96-7)
- 1-(3-Cyanophenyl)cyclobutane-1-carboxylic acid (CAS 1314744-75-6)
- Decanoic (S)-2-methyl-4-oxopyrrolidine-2-carboxylic anhydride (CAS 918883-28-0)
- (3,4-Dichloro-benzenesulfonylamino)-acetic acid (CAS 129582-99-6)
- 3-phenyl-octahydrocyclopenta[b]pyrrole (CAS 1053170-20-9)
- (e)-2-Amino-5-phenylpent-4-en-1-ol (CAS 1261024-78-5)
- 4-chloro-3,8-dimethylquinoline (CAS 39593-12-9)
- Macrocyclic Peptide flaviviridae Viruses InhibitorDISCONTINUED (CAS 1510840-70-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com