Metronidazole CAS 443-48-1
| CAS No. | 443-48-1 |
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metronidazole.
Metronidazole (CAS 443-48-1), molecular formula C6H9N3O3 and molecular weight 171.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Metronidazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 171.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Metronidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Metronidazole Standards
- Metronidazole Impurity 15 (CAS 110578-73-9)
- Metronidazole Impurity 18 (CAS 113385-77-6)
- Metronidazole EP Impurity E (CAS 705-19-1)
- Metronidazole Impurity N30 (CAS 56910-52-2)
- Metronidazole-d3 (CAS 83413-09-6)
- Metronidazole-13C2,15N2 (CAS 1173020-03-5)
- Metronidazole-d4 (CAS 1261392-47-5)
- Metronidazole Impurity 27 (CAS 34916-84-2)
Recommended Standards
- HISTIDINE Impurity 6 (CAS 1932060-69-9)
- 2,4,6-Trimethoxy-1,3,5-Triazine (CAS 877-89-4)
- HISTIDINE impurity 3 (CAS CATO-C4X-32393)
- H-6-Diazo-5-oxo-D-Nle-OH (CAS 71629-86-2)
- (+/-)-4-but-3-en-1-ylazetidin-2-one 4-(but-3-en-1-yl)azetidin-2-one 74373-13-0 (CAS 74373-13-0)
- 3-Bromo-n-n-propylbenzenesulfonamide (CAS 851172-93-5)
- Cerium(III) chloride hydrate (CAS 64332-99-6)
- 8-(2,5-Dimethoxyphenyl)-6-methyl-3,4,5,8-tetrahydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile (CAS 860644-72-0)
- 5-Acetyl-7-methyl-1,2-dihydrocyclopenta[b]indol-3(4H)-one (CAS 830347-28-9)
- methyl 2-(trifluoromethyl)-1H-pyrrole-3-carboxylate (CAS 2110344-75-5)
- 2-[N-(2,4-Dichloro-5-methoxyphenyl)4-fluorobenzenesulfonamido]-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 338967-36-5)
- (S)-1-(thiazol-4-yl)ethan-1-amine (CAS 1344637-19-9)
- α-D-Glucose-1-6-diphosphate potassium salt hydrate (CAS 91183-87-8)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com