Olopatadine Impurity N1 CAS 203188-31-2
| CAS No. | 203188-31-2 |
| Molecular Formula | C21H23NO4 |
| Molecular Weight | 353.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Olopatadine Impurity N1 (CAS 203188-31-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23NO4 and a molecular weight of 353.41 g/mol.
The molecular framework of Olopatadine Impurity N1 (C21H23NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Olopatadine Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23NO4 |
| Molecular Weight | 353.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Nitrogen Atoms | 1 |
Related Olopatadine Standards
- Olopatadine USP Related Compound B (CAS 173174-07-7)
- Olopatadine Impurity 69 (CAS CATO-C4X-171869)
- Olopatadine Impurity 49 (CAS CATO-C4X-171849)
- Olopatadine Impurity 51 (CAS 113806-01-2)
- Olopatadine Impurity 52 (CAS 949141-21-3)
- Olopatadine Impurity 73 (CAS CATO-C4X-171873)
- Olopatadine-d3 N-Oxide (CAS 1246832-94-9)
- Olopatadine Amide (CAS 872041-02-6)
Recommended Standards
- N-(benzo[d][1,3]dioxol-5-yl)-2-(4-benzylpiperazin-1-yl)acetamide (CAS 303091-35-2)
- o-Tolyl 8-methyl-2-phenylquinoline-4-carboxylate (CAS 355421-34-0)
- N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 329779-29-5)
- Phenyl 6-methyl-2-(p-tolyl)quinoline-4-carboxylate (CAS 355419-81-7)
- Folic Acid Impurity 63 (CAS CATO-C4X-139563)
- Meropenem EP Impurity B2 (CAS CATO-C4X-130921)
- Perindopril Impurity 101 (CAS CATO-C4X-1252101)
- 2-Amino-4-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 33081-06-0)
- 5,7-dioxo-1,4,8,11-tetra-azacyclo-tetradecane (CAS 63972-19-0)
- (4-Bromo-6-(difluoromethyl)-3-methylpyridin-2-yl)methanol (CAS 1806862-27-0)
- N-Methyl-1-(4-(trifluoromethyl)phenyl)methanamine (CAS 90390-11-7)
- 4H-Benzo[b][1,4]thiazine-2-carbonitrile (CAS 889877-07-0)
- 2-Ethoxy-4-methyl-5-nitropyridine (CAS 1881331-60-7)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com