Amlodipine Besylate EP Impurity D CAS 113994-41-5
| CAS No. | 113994-41-5 |
| Molecular Formula | C20H23ClN2O5 |
| Molecular Weight | 406.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 406.86 g/mol gives Amlodipine Besylate EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Amlodipine Besylate EP Impurity D (CAS 113994-41-5) is a certified pharmaceutical impurity reference standard with the molecular formula C20H23ClN2O5 and a molecular weight of 406.86 g/mol.
Amlodipine Besylate EP Impurity D (C20H23ClN2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amlodipine Besylate EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23ClN2O5 |
| Molecular Weight | 406.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Metabolite 5 (CAS 114018-75-6)
- Amlodipine (S)-Isomer (CAS 103129-82-4)
- Amlodipine (CAS 88150-42-9)
- (R)-Amlodipine (CAS 103129-81-3)
- Amlodipine para-Chloro Impurity (CAS 90445-02-6)
- Amlodipine Impurity 150 (CAS CATO-C4X-1095150)
- (S)-Amlodipine-d4 (CAS 1346617-19-3)
- Amlodipine-d4 (CAS 1185246-14-3)
Recommended Standards
- N-(3-(6-Chlorobenzo[d]oxazol-2-yl)-5-methylphenyl)-4-ethoxybenzamide (CAS 590396-53-5)
- Avanafil Impurity 124 (CAS CATO-C4X-1118124)
- 5-(3-Chlorobenzylidene)-3-((6-methoxy-2-methylquinolin-4-yl)amino)-2-methyl-3,5-dihydro-4H-imidazol-4-one (CAS 85986-74-9)
- Landiolol Impurity 132 (CAS CATO-C4X-2621132)
- Ponatinib Impurity 37 (CAS 2098039-04-2)
- Sorafenib Impurity 34 (CAS 121-50-6)
- Emedastine impurity 36 (CAS CATO-C4X-226736)
- 6-Bromo-2,3,4-trifluorobenzonitrile (CAS 2407339-61-9)
- 1-(3,5-Dimethylbenzoyl)piperazine (CAS 923163-82-0)
- 3-Chloro-7-isopropoxy-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1437434-27-9)
- 2-Chloro-3-fluoro-5-propoxypyridine (CAS 1353776-91-6)
- 2-(Bromomethyl)-1-nitro-4-(trifluoromethyl)benzene (CAS 133605-28-4)
- 2-(Benzo[d]isoxazol-3-yl)benzaldehyde (CAS 198967-18-9)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com