Cabozantinib Malate CAS 1140909-48-3
| CAS No. | 1140909-48-3 |
| Molecular Formula | C28H24FN3O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cabozantinib Malate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cabozantinib Malate (CAS 1140909-48-3), a certified reference material (molecular formula C28H24FN3O5C4H6O5, MW 635.60 g/mol) for analytical method development and quality control.
Structurally, Cabozantinib Malate (C28H24FN3O5C4H6O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 635.60 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H24FN3O5 C4H6O5 |
| Molecular Weight | 635.60 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cabozantinib Standards
- Cabozantinib Impurity N2 (CAS 113136-79-1)
- Cabozantinib Impurity 4 (CAS 1247859-37-5)
- Cabozantinib Impurity 40 (CAS 1275738-77-6)
- Cabozantinib 4-Fluorocarbamoyl Methyl Ester Impurity (CAS 1345847-71-3)
- Cabozantinib Impurity 3 (CAS 1431468-36-8)
- Cabozantinib Impurity 12 (CAS 145591-80-6)
- Cabozantinib N-oxide (CAS 1621681-63-7)
- Cabozantinib Impurity N1 (CAS 1628530-38-0)
Recommended Standards
- 4-Cyclopropoxy-3-isopropylaniline (CAS 1243467-14-2)
- 4-[2-(Dimethylamino)ethoxy]phenylboronic Acid Pinacol Ester (CAS 873078-93-4)
- 8-Nitro-3,4-dihydronaphthalen-1(2H)-one (CAS 58161-31-2)
- (S)-2-hydroxypropyl methanesulfonate (CAS 262423-83-6)
- 7-Methyl-1H-pyrrolo[2,3-c]pyridine-2,3-dicarboxylic acid (CAS 58795-15-6)
- tert-Butyl ((4-carbamoyltetrahydro-2H-pyran-4-yl)methyl)carbamate (CAS 1387936-82-4)
- 7-Chloro-2-(2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 862663-10-3)
- 1-(2-Chloro-4-nitrophenyl)piperidine hydrochloride (CAS 1049750-07-3)
- 2-(5-Benzyloxy-2-methoxyphenoxy)-ethylamine 2-[2-Methoxy-5-(phenylmethoxy)phenoxy]ethanamine 887353-08-4 (CAS 887353-08-4)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com