Cabozantinib N-oxide CAS 1621681-63-7
| CAS No. | 1621681-63-7 |
| Molecular Formula | C28H24FN3O6 |
| Molecular Weight | 517.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cabozantinib N-oxide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cabozantinib N-oxide (CAS 1621681-63-7), a certified reference material (molecular formula C28H24FN3O6, MW 517.51 g/mol) for analytical method development and quality control.
The molecular framework of Cabozantinib N-oxide (C28H24FN3O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Cabozantinib N-oxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H24FN3O6 |
| Molecular Weight | 517.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cabozantinib Standards
- Cabozantinib Impurity N1 (CAS 1628530-38-0)
- Cabozantinib Impurity 36 (CAS 1628530-41-5)
- Cabozantinib-d6 (CAS 1802168-46-2)
- Cabozantinib-d4 (CAS 1802168-53-1)
- Cabozantinib Impurity 47 (CAS CATO-C4X-201847)
- Cabozantinib (CAS 849217-68-1)
- Cabozantinib Impurity 17 (CAS CATO-C4X-201817)
- Cabozantinib Impurity 13 (CAS 849221-94-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com