Baclofen EP Impurity C CAS 35271-74-0
| CAS No. | 35271-74-0 |
| Molecular Formula | C11H11ClO4 |
| Molecular Weight | 242.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Baclofen EP Impurity C is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Baclofen EP Impurity C (CAS 35271-74-0) is a certified pharmaceutical impurity reference standard with the molecular formula C11H11ClO4 and a molecular weight of 242.66 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Baclofen EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClO4 |
| Molecular Weight | 242.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
Related Baclofen Standards
- Baclofen impurity 7 (CAS 103857-58-5)
- Baclofen impurity 12 (CAS 232597-00-1)
- Baclofen impurity 4 (CAS 159112-23-9)
- Baclofen EP Impurity B (CAS 1141-23-7)
- Baclofen Impurity 37 (CAS CATO-C4X-101237)
- Baclofen Impurity 38 (CAS CATO-C4X-101238)
- Baclofen Impurity 41 (CAS 159156-84-0)
- Baclofen impurity 18 (CAS CATO-C4X-101218)
Recommended Standards
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- Losartan Impurity 22 (CAS 39739-46-3)
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- 3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yloxy)benzoic acid (CAS 1269527-51-6)
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- Esmolol Impurity 13 (CAS CATO-C4X-189113)
- 2-Fluoro-3,4-dimethylaniline (CAS 1535387-53-1)
- (5-(3-Fluorophenyl)pyridin-3-yl)methanamine (CAS 1356110-47-8)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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