Telmisartan Impurity 33 CAS 114772-34-8
| CAS No. | 114772-34-8 |
| Molecular Formula | C15H14O2 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C15H14O2, Telmisartan Impurity 33 contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Telmisartan Impurity 33 (CAS 114772-34-8, C15H14O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Telmisartan Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14O2 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Telmisartan Standards
- Telmisartan Aldehyde Impurity (CAS 112804-58-7)
- Telmisartan Impurity 10 (CAS 136304-93-3)
- Telmisartan Impurity 31 (CAS 158144-54-8)
- Telmisartan Impurity 98 (CAS CATO-C4X-135998)
- Telmisartan Impurity 99 (CAS CATO-C4X-135999)
- Telmisartan Impurity 59 (CAS 1016696-74-4)
- Telmisartan Impurity 69 (CAS CATO-C4X-135969)
- Telmisartan Impurity 13 (CAS 152628-00-7)
Recommended Standards
- Temozolomide Impurity 26 (CAS 13114-72-2)
- Metoprolol Impurity 27 (CAS 40167-10-0)
- Propafenone Impurity 29 (CAS 36941-00-1)
- Metoprolol EP Impurity D (CAS 62572-90-1)
- Relmapirazin impurity 45 (CAS CATO-C4X-33345)
- Levocetirizine Impurity 8 (CAS 83881-46-3)
- Rimegepant Impurity 160 (CAS CATO-C4X-2487160)
- 5-Iodo-2-trifluoromethoxyphenylboronic acid (CAS 1256355-12-0)
- Ketoprofen D-Lysinate (CAS 1544601-57-1)
- Melphalan Impurity 32 (CAS CATO-C4X-198832)
- 2-Amino-4-(difluoromethyl)-5-fluoronicotinaldehyde (CAS 1804728-06-0)
- 5-bromo-3-methoxy-imidazo[1,2-d][1,2,4]thiadiazole (CAS 2763448-69-5)
- N-Desmethyl Tramadol-d3 HCl (CAS 1261398-09-7)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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