Propafenone Impurity 29 CAS 36941-00-1
| CAS No. | 36941-00-1 |
| Molecular Formula | C15H14O2 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Propafenone Impurity 29.
Propafenone Impurity 29 (CAS 36941-00-1) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14O2 and a molecular weight of 226.27 g/mol.
Structurally, Propafenone Impurity 29 (C15H14O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 226.27 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Propafenone Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14O2 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
Related Propafenone Standards
- Propafenone EP Impurity A (CAS 3516-95-8)
- Propafenone Impurity 28 (CAS CATO-C4X-132228)
- Propafenone Impurity 31 (CAS CATO-C4X-132231)
- Propafenone Impurity 30 (CAS 17002-31-2)
- Propafenone EP Impurity H(R-isomer) (CAS 27439-12-9)
- Propafenone EP Impurity H (CAS 487-26-3)
- Propafenone RC 6 (CAS 189766-45-8)
- Propafenone Impurity 23 (CAS CATO-C4X-132223)
Recommended Standards
- Temozolomide Impurity 26 (CAS 13114-72-2)
- Telmisartan Impurity 33 (CAS 114772-34-8)
- Terbutaline Impurity 51 (CAS 34068-01-4)
- Metoprolol Impurity 27 (CAS 40167-10-0)
- Docetaxel Impurity 64 (CAS CATO-C4X-161964)
- Velpatasvir Impurity 12 (CAS CATO-C4X-289412)
- Eltrombopag Impurity 90 (CAS CATO-C4X-119890)
- 2,3-Diamino-N-(4-fluoro-3-(trifluoromethyl)phenyl)benzamide (CAS 1421933-30-3)
- Tedizolid Impurity 63 (CAS 626-55-1)
- tert-butyl N-[(1R,2R)-2-methanesulfonamidocyclohexyl]carbamate (CAS 1807938-41-5)
- Boc-(2R,5S)-5-phenylpyrrolidine-2-carboxylic acid (CAS 158706-46-8)
- Glutaric Acid (CAS 110-94-1)
- 4-[5-(3,4-Dimethoxyphenyl)-2H-tetrazol-2-yl]piperidine hydrochloride (CAS 1052518-26-9)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
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