Carbidopa EP Impurity B Hydrochloride CAS 115054-62-1
| CAS No. | 115054-62-1 |
| Molecular Formula | C11H15NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Carbidopa EP Impurity B Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Carbidopa EP Impurity B Hydrochloride (CAS 115054-62-1), a pharmacopoeial impurity reference standard (molecular formula C11H15NO4HCl, MW 261.70 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Carbidopa EP Impurity B Hydrochloride (C11H15NO4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H15NO4 HCl |
| Molecular Weight | 261.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Carbidopa Standards
- Carbidopa Impurity 36 (CAS 1026009-73-3)
- rac-Carbidopa EP Impurity I (CAS 1246819-09-9)
- (S)-(-)-Carbidopa-d3 H2O (ring-d3) (CAS 1276197-58-0)
- Carbidopa-d3 (CAS 1276732-89-8)
- Carbidopa EP Impurity H (CAS 1361017-74-4)
- (S)-(-)-Carbidopa-d5 (CAS 1426174-03-9)
- Carbidopa EP Impurity F (CAS 1458640-32-8)
- Carbidopa EP Impurity B (CAS 18181-08-3)
Recommended Standards
- Finerenone Impurity 200 (CAS CATO-C4X-2880200)
- Glutathione impurity 20 (CAS 70555-25-8)
- (E)-Ramelteon Impurity 11 (CAS 196597-61-2)
- 2-Bromo-6-iodobenzoic acid (CAS 1022128-96-6)
- Guanfacine-13C,15N3 (CAS 1189924-28-4)
- 2-(Pyrrolidin-1-ylmethyl)azepane (CAS 112282-41-4)
- (R)-2-Amino-2-(naphthalen-2-yl)acetic acid hydrochloride (CAS 1393112-57-6)
- AMPK activator SC4 (CAS 1364692-88-5)
- 4-Chloro-5-(difluoromethoxy)pyrimidine (CAS 1261737-58-9)
- Vialox Peptide(Pentapeptide-3) diacetate (CAS 725232-44-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com