Roflumilast Impurity 10 CAS 127842-54-0

Description

Compared with other compounds in its class, the molecular weight of 238.14 g/mol gives Roflumilast Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Roflumilast Impurity 10 (CAS 127842-54-0), a pharmacopoeial impurity reference standard (molecular formula C9H6F4O3, MW 238.14 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Roflumilast Impurity 10 (C9H6F4O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Roflumilast Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
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• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com