Paclitaxel Impurity 17 (7-(Triethylsilyl)baccatin III) CAS 115437-21-3
| CAS No. | 115437-21-3 |
| Molecular Formula | C37H52O11Si |
| Molecular Weight | 700.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Paclitaxel Impurity 17 (7-(Triethylsilyl)baccatin III) (CAS 115437-21-3), molecular formula C37H52O11Si and molecular weight 700.89 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Paclitaxel Impurity 17 (7-(Triethylsilyl)baccatin III) is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 700.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C37H52O11Si |
| Molecular Weight | 700.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Paclitaxel Standards
- Paclitaxel Impurity 17(13-O-(Triethylsilyl) Baccatin III) (CAS 208406-86-4)
- Paclitaxel Impurity 32 (Baccatin VI) (CAS 57672-79-4)
- Paclitaxel Impurity 21 (CAS 30244-37-2)
- Paclitaxel Impurity 60 (CAS CATO-C4X-184260)
- Paclitaxel EP Impurity G (CAS 78432-77-6)
- Paclitaxel EP Impurity H (CAS 78454-17-8)
- Paclitaxel Impurity 54 (CAS CATO-C4X-184254)
- Paclitaxel EP Impurity N (CAS 27548-93-2)
Recommended Standards
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