Paclitaxel Impurity 17(13-O-(Triethylsilyl) Baccatin III) CAS 208406-86-4
| CAS No. | 208406-86-4 |
| Molecular Formula | C37H52O11Si |
| Molecular Weight | 700.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Paclitaxel Impurity 17(13-O-(Triethylsilyl) Baccatin III) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Paclitaxel Impurity 17(13-O-(Triethylsilyl) Baccatin III) (CAS 208406-86-4) is a certified pharmaceutical impurity reference standard with the molecular formula C37H52O11Si and a molecular weight of 700.89 g/mol.
Structurally, Paclitaxel Impurity 17(13-O-(Triethylsilyl) Baccatin III) (C37H52O11Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 700.89 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C37H52O11Si |
| Molecular Weight | 700.89 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2016 |
Related Paclitaxel Standards
- Paclitaxel Impurity 17 (7-(Triethylsilyl)baccatin III) (CAS 115437-21-3)
- Paclitaxel Impurity 32 (Baccatin VI) (CAS 57672-79-4)
- Paclitaxel Impurity 21 (CAS 30244-37-2)
- Paclitaxel Impurity 60 (CAS CATO-C4X-184260)
- Paclitaxel EP Impurity G (CAS 78432-77-6)
- Paclitaxel EP Impurity H (CAS 78454-17-8)
- Paclitaxel Impurity 54 (CAS CATO-C4X-184254)
- Paclitaxel EP Impurity N (CAS 27548-93-2)
Recommended Standards
- (R)-5-(tert-Butoxy)-5-oxo-4-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanoic acid (CAS 817562-90-6)
- Ilaprazole Impurity 26 (CAS 2285346-41-8)
- 5-(tert-Butoxy)-5-oxo-4-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanoic acid (CAS 306776-79-4)
- (R)-Xyl-SDP (CAS 917377-75-4)
- Fenfluramine Impurity 5 HCl (CAS 54779-55-4)
- Promethazine EP Impurity B HCl (CAS 5568-90-1)
- Foritinib Impurity 13 (CAS CATO-C4X-331013)
- 6-Aminoquinoxaline-5-carbonitrile (CAS 130278-26-1)
- 2-Methoxy-N-(3-methoxybenzyl)ethan-1-amine (CAS 827327-99-1)
- 6-Methyl-2-(4-methylpiperazin-1-yl)pyrimidin-4-ol (CAS 1685-68-3)
- 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one (CAS 118877-07-9)
- 2-Bromobenzothiazol-4-ol (CAS 1260385-62-3)
- Hydroxy Mifepristone D6 (CAS 105012-15-5 (Unlabelled))
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com