Paclitaxel EP Impurity G CAS 78432-77-6
| CAS No. | 78432-77-6 |
| Molecular Formula | C45H49NO13 |
| Molecular Weight | 811.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Paclitaxel EP Impurity G (CAS 78432-77-6) is a certified pharmaceutical impurity reference standard with the molecular formula C45H49NO13 and a molecular weight of 811.87 g/mol.
Structurally, Paclitaxel EP Impurity G (C45H49NO13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 22.0, corresponding to approximately 22 ring(s) or double-bond equivalent(s). With a molecular weight of 811.87 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Paclitaxel EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C45H49NO13 |
| Molecular Weight | 811.87 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
Related Paclitaxel Standards
- Paclitaxel EP Impurity H (CAS 78454-17-8)
- Paclitaxel Impurity 36 (CAS 153415-46-4)
- Paclitaxel EP Impurity A (CAS 173101-54-7)
- Paclitaxel Impurity 18 (CAS CATO-C4X-184218)
- Paclitaxel EP Impurity B (CAS 71610-00-9)
- Paclitaxel EP Impurity D (CAS 150547-36-7)
- Paclitaxel EP Impurity R (CAS 158948-96-0)
- Paclitaxel Impurity R (CAS 159001-25-9)
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