Paclitaxel EP Impurity H CAS 78454-17-8
| CAS No. | 78454-17-8 |
| Molecular Formula | C45H49NO13 |
| Molecular Weight | 811.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Paclitaxel EP Impurity H (C45H49NO13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Paclitaxel EP Impurity H (CAS 78454-17-8), a pharmacopoeial impurity reference standard (molecular formula C45H49NO13, MW 811.87 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Paclitaxel EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C45H49NO13 |
| Molecular Weight | 811.87 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
Related Paclitaxel Standards
- Paclitaxel EP Impurity G (CAS 78432-77-6)
- Paclitaxel Impurity 36 (CAS 153415-46-4)
- Paclitaxel EP Impurity A (CAS 173101-54-7)
- Paclitaxel Impurity 18 (CAS CATO-C4X-184218)
- Paclitaxel EP Impurity B (CAS 71610-00-9)
- Paclitaxel EP Impurity D (CAS 150547-36-7)
- Paclitaxel EP Impurity R (CAS 158948-96-0)
- Paclitaxel Impurity R (CAS 159001-25-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com