Diltiazem USP Related Compound H HCl CAS 115992-91-1(Free Base)
| CAS No. | 115992-91-1(Free Base) |
| Molecular Formula | C17H18N2O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Diltiazem USP Related Compound H HCl (CAS 115992-91-1(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C17H18N2O3SHCl, MW 366.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Diltiazem USP Related Compound H HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Diltiazem USP Related Compound H HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18N2O3S HCl |
| Molecular Weight | 366.86 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem EP Impurity A HCl (CAS 103532-27-0)
- Diltiazem EP Impurity A HCl (CAS 111188-71-7(free base))
- Diltiazem D4 (CAS 112259-41-3)
- Diltiazem EP Impurity H HCl (CAS 115992-91-1(free base))
- Diltiazem Impurity 9 (CAS 116050-35-2)
- Diltiazem Impurity 23 (CAS 119009-50-6)
- Diltiazem-d3 Hydrochloride (CAS 1217623-80-7)
- L-Diltiazem (CAS 1217650-51-5)
Recommended Standards
- Canagliflozin Impurity 3 (CAS CATO-C4X-11233)
- Bisacodyl Impurity 11 (CAS CATO-C4X-203711)
- Papaverine Impurity 12 (CAS 33520-96-6（free base）)
- 2,2,2-Trifluoro-N-(2-hydroxy-3,5-dinitrophenethyl)acetamide (CAS 1161880-89-2)
- (Z)-{2-[(4-chlorophenyl)sulfanyl]-1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene}[(2,4-dichlorophenyl)methoxy]amine (CAS 478047-78-8)
- SB-277011A hydrochloride, >98% (HPLC) (CAS 215804-67-4)
- 1,3-Dichlorotetrafluorobenzene (CAS 1198-61-4)
- N-Benzyl-3-bromo-5-methylbenzenesulfonamide (CAS 1020252-85-0)
- 2-(4-Chloro-3-methylphenyl)tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione (CAS 58744-51-7)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com