Podophyllotoxin impurity 5 CAS 1174-97-6
| CAS No. | 1174-97-6 |
| Molecular Formula | C21H22O8 |
| Molecular Weight | 402.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Podophyllotoxin impurity 5 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Podophyllotoxin impurity 5 (CAS 1174-97-6) is a certified pharmaceutical impurity reference standard with the molecular formula C21H22O8 and a molecular weight of 402.39 g/mol.
Podophyllotoxin impurity 5 (C21H22O8) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Podophyllotoxin impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22O8 |
| Molecular Weight | 402.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Podophyllotoxin Standards
- Podophyllotoxin 4-Deoxy 5-Bromo 6,7-Dihydroxy (CAS 93108-15-7)
- Podophyllotoxin Impurity N2 (CAS 42123-27-3)
- Podophyllotoxin EP Impurity C (CAS 477-49-6)
- Podophyllotoxin impurity 4 (CAS 138456-91-4)
- Podophyllotoxin Impurity 1 (CAS 1173-42-8)
- Podophyllotoxin impurity 7 (CAS CATO-C4X-24257)
- Podophyllotoxin Impurity 8 (CAS 16481-54-2)
Recommended Standards
- tert-butyl N-[2-(difluoromethoxy)-4-[3-(dimethylamino)azetidin-1-yl]-5-nitrophenyl]carbamate (CAS 2244285-46-7)
- Nobiletin (CAS 478-01-3)
- N'-(9H-Fluoren-9-ylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2553409-21-3)
- 5,6,7,3',4',5'-Hexamethoxyflavone (CAS 29043-07-0)
- Cefotiam Impurity 16 (CAS 1628441-07-5(Free Base))
- Montelukast Impurity N3 (CAS 880769-28-8)
- Tetrabenazine Impurity 15 (CAS 1256550-62-5)
- (5-Cyano-2-fluorophenyl)methanesulfonyl Chloride (CAS 1258651-01-2)
- 9-Phenyl-1,2,3,4-tetrahydroacridine (CAS 10265-83-5)
- Cyclopentyl 4-(4-chloro-3-nitrophenyl)-7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 503591-50-2)
- Ethyl 6-methoxy-2,3-dihydro-1H-pyrrolo[3,2-b]quinoline-1-carboxylate (CAS 34086-71-0)
- (6-Chloro-4-(difluoromethyl)-5-methylpyridin-2-yl)methanol (CAS 1806872-04-7)
- [4-(3-Chlorophenyl)-1-piperazinyl][3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone (CAS 933202-27-8)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com