Podophyllotoxin EP Impurity C CAS 477-49-6
| CAS No. | 477-49-6 |
| Molecular Formula | C22H20O8 |
| Molecular Weight | 412.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Podophyllotoxin EP Impurity C.
Podophyllotoxin EP Impurity C (CAS 477-49-6) is a certified pharmaceutical impurity reference standard with the molecular formula C22H20O8 and a molecular weight of 412.39 g/mol.
Podophyllotoxin EP Impurity C (C22H20O8) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Podophyllotoxin EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H20O8 |
| Molecular Weight | 412.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Podophyllotoxin Standards
- Podophyllotoxin Impurity N2 (CAS 42123-27-3)
- Podophyllotoxin impurity 5 (CAS 1174-97-6)
- Podophyllotoxin 4-Deoxy 5-Bromo 6,7-Dihydroxy (CAS 93108-15-7)
- Podophyllotoxin impurity 4 (CAS 138456-91-4)
- Podophyllotoxin Impurity 1 (CAS 1173-42-8)
- Podophyllotoxin impurity 7 (CAS CATO-C4X-24257)
- Podophyllotoxin Impurity 8 (CAS 16481-54-2)
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- Potassium (1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)trifluoroborate (CAS 1492904-33-2)
- 4'-(2-Methylbutyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 67004-59-5)
- Nimodipine Impurity 60 (CAS CATO-C4X-138560)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com