Resmetirom impurity 80 CAS CATO-C4X-291280
| CAS No. | CATO-C4X-291280 |
| Molecular Formula | C13H14ClN3O2 |
| Molecular Weight | 279.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 279.72 g/mol gives Resmetirom impurity 80 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Resmetirom impurity 80 (CAS CATO-C4X-291280) is a certified pharmaceutical impurity reference standard with the molecular formula C13H14ClN3O2 and a molecular weight of 279.72 g/mol.
Resmetirom impurity 80 (C13H14ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Resmetirom impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14ClN3O2 |
| Molecular Weight | 279.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom impurity 76 (CAS CATO-C4X-291276)
- Resmetirom impurity 94 (CAS CATO-C4X-291294)
- Resmetirom impurity 121 (CAS CATO-C4X-2912121)
- Resmetirom Impurity 8 (CAS 1581304-46-2)
- Resmetirom Impurity 43 (CAS CATO-C4X-291243)
- Resmetirom impurity 74 (CAS 116688-45-0)
- Resmetirom Impurity 62 (CAS CATO-C4X-291262)
- Resmetirom impurity 66 (CAS CATO-C4X-291266)
Recommended Standards
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- Domperidone EP Impurity B (CAS 1346598-11-5)
- Blonanserin Impurity 9 dihydrochloride (CAS 49860-76-6)
- Indometacin Impurity 55 (CAS CATO-C4X-147055)
- Rupatadine Impurity 38 (CAS CATO-C4X-102738)
- tert-butyl (2S)-2-methyl-3-oxoazetidine-1-carboxylate (CAS 171919-76-9)
- 2-Hydroxy-1-morpholino-2-phenylethan-1-one (CAS 57872-39-6)
- 3-Chloro-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 103589-67-9)
- (2S,3R)-N-(tert-Butyloxycarbonyl)-3-methyl-pyroglutaminol (CAS 910548-24-2)
- 1-(Piperazin-1-yl)-2-(p-tolyl)ethan-1-one hydrochloride (CAS 1240527-10-9)
- 2-(3,5-Dimethoxyphenyl)cyclopropanecarbaldehyde (CAS 1708288-75-8)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com