Rabeprazole Impurity 41 CAS 117977-18-1
| CAS No. | 117977-18-1 |
| Molecular Formula | C11H17NO3 |
| Molecular Weight | 211.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rabeprazole Impurity 41 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Rabeprazole Impurity 41 (CAS 117977-18-1), a pharmacopoeial impurity reference standard (molecular formula C11H17NO3, MW 211.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Rabeprazole Impurity 41 (C11H17NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H17NO3 |
| Molecular Weight | 211.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Rabeprazole Standards
- Rabeprazole Impurity 24 (CAS 118175-10-3)
- Rabeprazole Impurity 23 (CAS 1260859-24-2)
- Rabeprazole Impurity 28 (CAS 40828-54-4)
- Rabeprazole Impurity 29 (CAS 1163685-31-1)
- Rabeprazole Impurity 52 (CAS 209914-29-4)
- Rabeprazole Impurity 35 (CAS 117977-20-5)
- Rabeprazole impurity 48 (CAS 92288-14-7)
- Rabeprazole Impurity 41 (CAS 924663-39-8)
Recommended Standards
- Ezetimibe Impurity 69 (CAS 6744-65-6)
- Sildenafil Impurity 41 (CAS 304435-83-4)
- b-Amino-3,4-dimethoxybenzenepropanol (CAS 19881-95-9)
- Oxcarbazepine Impurity 27 (CAS 4014-77-1)
- Melitracen Impurity 6 (CAS 18792-73-9)
- Dabigatran Impurity 131 (CAS 429658-95-7)
- Levofloxacin Impurity 32 (CAS 1329833-82-0)
- TBdms-peg5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite (CAS 1807521-08-9)
- ((5-Carboxy-2-chlorophenyl)sulfonyl)proline (CAS 1008580-51-5)
- N-(5-Chloro-2-methylphenyl)-5-methylisoxazole-4-carboxamide (CAS 61669-23-6)
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, (1R,4S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate (1:1) (CAS 120202-68-8)
- [1,3]dioxolo[4,5-β]pyridine (CAS 72138-73-9)
- 2-(5-Bromo-1,3-dioxoisoindolin-2-yl)-3-methylbutanoic acid (CAS 355813-55-7)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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