Dabigatran Impurity 131 CAS 429658-95-7
| CAS No. | 429658-95-7 |
| Molecular Formula | C27H29N7O3 |
| Molecular Weight | 499.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dabigatran Impurity 131 (C27H29N7O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Dabigatran Impurity 131 (CAS 429658-95-7, C27H29N7O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dabigatran Impurity 131 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H29N7O3 |
| Molecular Weight | 499.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 7 |
Related Dabigatran Standards
- Dabigatran Impurity 30 (CAS 948551-71-1)
- Dabigatran Impurity 8 (CAS 1422435-41-3)
- Dabigatran Impurity 91 (CAS CATO-C4X-108991)
- Dabigatran Impurity 120 (CAS CATO-C4X-1089120)
- Dabigatran Methyl Ester Impurity (CAS 771459-37-1)
- Dabigatran Isopropyl Ester Impurity (CAS 1610758-17-2)
- Dabigatran Impurity 12 (CAS CATO-C4X-108912)
- Dabigatran Impurity 26 (CAS 211915-84-3)
Recommended Standards
- 2-(Diphenylphosphino)-N-[2-(diphenylphosphino)ethyl]-N-(2-methoxyethyl)ethanamine (CAS 30853-94-2)
- tert-butyl 3-(5-(3-cyano-6-(3,6-dihydro-2H-pyran-4-yl)pyrazolo[1,5-a]pyridin-4-yl)pyrazin-2-yl)-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate (CAS CATO-C3D-262142)
- (S)-Methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanamido)-3-phenylpropanoate (CAS 63328-40-5)
- N-Nitroso Vilazodone Ethyl Ester Impurity 12 (CAS CATO-C4X-135512)
- Esomeprazole Impurity 95 (CAS CATO-C4X-111295)
- Riociguat Impurity 2 (CAS 1361569-10-9)
- Topiramate EP Impurity E (D-fructopyranose) (CAS 6347-01-9)
- N-(furan-2-ylmethyl)pyrrolidine-2-carboxamide hydrochloride (CAS 1078162-92-1)
- Methyl 5-Bromo-7-fluoroindole-3-carboxylate (CAS 1360951-29-6)
- 4-(1,5-Diazabicyclo(3.2.1)oct-8-yl)-pyridine (CAS 13022-80-5)
- 3-(3-(Trifluoromethyl)phenyl)pyrrolidine-2,5-dione (CAS 60050-38-6)
- 4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine (CAS 194669-46-0)
- 1-((4-Vinylbenzyl)oxy)anthracene-9,10-dione (CAS 88769-49-7)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com